PGM Lab Laboratory for Precision Genome Medicine

Projects and Funding

Below are the main projects and funding sources.

Development of Nanopore Sequencing-Based Genomic Analysis and Diagnostic Technologies for Clinical Application
Principal Investigator

Development of Nanopore Sequencing-Based Genomic Analysis and Diagnostic Technologies for Clinical Application

Grant No.
RS-2025-02214700
Funding Period
Apr 1, 2025 – Dec 31, 2027
Total Budget
550,000,000 KRW

We aim to establish a robust diagnostic infrastructure by:

  • Building a Korean reference genome database
  • Developing advanced data analysis pipelines
  • Designing and evaluating disease-specific gene panels

Through these efforts, we will validate the clinical utility of nanopore sequencing technology.

Funding Source: Global Physician-Scientist Development Program for Early-Career Physician-Scientists, Korea Health Industry Development Institute (KHIDI)
META-Center (Metastasis Targeting and Analysis Center)
Co-Investigator

Elucidating the Mechanisms of Cancer Metastasis through Time-Series Multi-Analysis and Developing Control Technologies

Grant No.
RS-2025-25459146
Funding Period
Aug 1, 2025 – Dec 31, 2029
Total Budget
6,625,000,000 KRW

The META-Center aims to uncover how cancer metastasis occurs. Our Group 3-2 team focuses on analyzing epigenomic changes in cancer tissues using long-read sequencing technologies.

META-Center Members
META-Center Members
Funding Source: Global Collaborative Research Support for Physician-Scientists, Korea Health Industry Development Institute (KHIDI)
Novel gene discovery and functional characterization in undiagnosed hereditary hearing loss
Co-Principal Investigator

Novel Gene Discovery and Functional Characterization in Undiagnosed Hereditary Hearing Loss Using Long-Read Sequencing

Grant No.
D-2025-0010
Funding Period
Sep 1, 2025 – Oct 31, 2026
Total Budget
50,000,000 KRW

In collaboration with Prof. Heon Yung Gee (Department of Pharmacology) and Prof. Jinsei Jung (Department of Otorhinolaryngology) at Yonsei University College of Medicine, we will investigate undiagnosed hereditary hearing loss cases to identify novel associated genes and variants using long-read sequencing technology.

Funding Source: Gangnam Severance Hospital, Yonsei University College of Medicine